What is FIP (feline infectious peritonitis) in cats?
FIP is a relatively rare but often fatal viral disease which is common in young cats (less than 2 years old) and kittens and is caused by an infection with the virus named feline coronavirus. It’s important to note that this is different from the coronavirus that infects people and leads to COVID-19. This is a feline coronavirus that is very common and only causes mild symptoms, but in a few cases, it mutates into the feline infectious peritonitis virus, triggering FIP, a serious disease that is deadly for most cats.
A mutated feline coronavirus can trigger feline infectious peritonitis, so before we get to the specifics of the FIP disease in cats, let’s look at what the feline coronavirus is and how your pet might get it.
What is the feline coronavirus?
The feline coronavirus affects cats and is not contagious to humans. However, it can easily transmit from feline to feline and it’s usually passed in cat faeces. This is why it’s more common in cats that are in close proximity with or share a household with other cats and are in contact with their litter trays.
The good news is that, despite being a very transmittable virus encountered by nearly every cat throughout their lives, feline coronavirus doesn’t typically make your cat visibly ill. The infection is normally limited to the intestinal tract, so if symptoms do manifest, they’re mild and you will usually notice your kitten suffering from diarrhoea for a few days and nothing more.
Why does feline coronavirus cause feline infectious peritonitis?
So how does a seemingly harmless virus turn into a more dangerous strain, capable of activating a disease that is fatal for most cats? As the feline coronavirus starts to replicate inside your cat’s body, mutations might occur. Scientists don’t know yet what is causing these mutations, but a weak immune system, stress and even age (with younger cats being more susceptible to FIP virus) have been proposed as possible explanations.
One of these mutations can turn the feline coronavirus into the feline infectious peritonitis virus which, instead of remaining confined to the intestinal tract, infects blood cells that then travel throughout the entire body. The immune system should be able to intervene at this point and fight off the infection, but if this does not happen, the cat will develop feline infectious peritonitis.
So, even if the cat becomes infected with the FIP virus, it does not necessarily follow that they will suffer from the FIP disease. A strong immune system will be able to stop the illness from being triggered. However, this means that young and old kittens with weaker immune responses are less likely to stop the virus and FIP will be triggered as a consequence. Despite this, the disease luckily remains quite rare in cats.